Key Points. Questions What is the 20-year prevalence of food insecurity among individuals with cardiovascular disease or cardiometabolic risk factors, and does this prevalence differ across racial and ethnic groups?. Findings In this cross-sectional study of noninstitutionalized US adults from 1999 through 2018, food insecurity increased over … Abstract Full Text. JAMA Cardiol. 2024;9 (3):263-271. doi:10.1001/jamacardio.2023.5366. This pooled cohort study assesses the risk of coronary heart disease associated with familial hypercholesterolemia variants in individuals with moderately to severely elevated low-density lipoprotein cholesterol. Mission Statement: JAMA Cardiology publishes exceptional original research, state-of-the-art reviews, and informative opinions that advance the science and practice of cardiology, enhance cardiovascular health, and inform health care policyJAMA Cardiology is the definitive journal for clinical investigators, clinicians, and trainees in cardiovascular medicine worldwide.Importance Increasing cardiology workforce diversity will expand the talent of the applicant pool and may reduce health care disparities.. Objective To assess US cardiology physician workforce demographics by sex and race/ethnicity in the context of the US population and the available pipelines of trainees.. Design, Setting, and Participants This cross-sectional study used data …van Diepen S, Fordyce CB, Wegermann ZK, et al. Organizational structure, staffing, resources, and educational initiatives in cardiac intensive care units in the United States: an American Heart Association Acute Cardiac Care Committee and American College of Cardiology Critical care Cardiology Working Group cross sectional survey.JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959)Key Points. Question Are initial and serial increases in high-sensitivity C-reactive protein levels after acute coronary syndrome in medically optimized patients associated with increased risk of a major cardiac event, cardiovascular death, and all-cause death?. Findings In this secondary analysis of the VISTA-16 randomized clinical trial that …JAMA Cardiology. Key Points. Question How many clinically significant variants for familial hypercholesterolemia would be missed by limited-variant screening conducted on microarrays? Findings In this cross-sectional review of comprehensive genetic test results for individuals with indications for familial hypercholesterolemia, a limited ...Introduction. In rural and regional settings, reperfusion therapy for ST-segment elevation myocardial infarction (STEMI) involves thrombolysis followed by transfer to a percutaneous coronary intervention (PCI)–capable hospital. 1, 2 Rapid and correct diagnosis is the first step in the chain of survival for patients with STEMI.In this issue of JAMA Cardiology, Liu et al 2 provide important new data from 2 secondary prevention samples (UK Biobank, N = 14 478; Emory Cardiovascular Biobank, N = 5467). The prevalence of very high HDL-C (>80 mg/dL) was low in both samples (<2%) and comprised a higher proportion of women and those reporting frequent alcohol use; low ...Key Points. Question Is the clinical benefit of low-density lipoprotein cholesterol (LDL-C) lowering preserved in patient populations starting with LDL-C levels averaging 1.8 mmol/L (70 mg/dL) or less, and is LDL-C lowering safe in such patients?. Findings In this meta-analysis, for statins and nonstatins, the risk of major vascular …In this issue of JAMA Cardiology, Liu et al 2 provide important new data from 2 secondary prevention samples (UK Biobank, N = 14 478; Emory Cardiovascular Biobank, N = 5467). The prevalence of very high HDL-C (>80 mg/dL) was low in both samples (<2%) and comprised a higher proportion of women and those reporting frequent alcohol use; low ...Importance Limited evidence suggests exercise reduces blood pressure (BP) in individuals with resistant hypertension, a clinical population with low responsiveness to drug therapy.. Objective To determine whether an aerobic exercise training intervention reduces ambulatory BP among patients with resistant hypertension.. Design, Settings, and … JAMA Cardiology—The Year in Review, 2023. Robert O. Bonow, MD, MS JAMA Cardiol March 13, 2024. Original Investigation. Quantitative Coronary Angiography vs ... Long-term use of a left ventricular assist device for end-stage heart failure. N Engl J Med. 2001;345 (20):1435-1443. PubMed Google Scholar Crossref. Miller LW, Pagani FD, Russell SD, et al; HeartMate II Clinical Investigators. Use of a continuous-flow device in …JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959)Key Points. Question In patients diagnosed with atrial fibrillation before 66 years of age, what is the prevalence of disease-associated variants in susceptibility genes for inherited cardiomyopathy and arrhythmia syndromes?. Findings In this cohort study, among 1293 participants who underwent whole genome sequencing, disease-associated rare …Key Points. Question What proportion of opioid-naive patients who undergo cardiac surgery have new persistent opioid use 90 days after surgery and is there an association with the amount of opioids prescribed at discharge?. …Importance The role of the coronary venous circulation in regulating myocardial perfusion and its potential in treating microvascular angina is unexplored.. Objective To evaluate whether an increase in coronary venous pressure modifies microvascular resistance in patients with microvascular angina.. Design, Setting, and Participants This was a blinded, sham-controlled, …Dec 6, 2022 · JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JAMA Cardiology publishes exceptional original research, state-of-the-art reviews, and informative opinions that advance the science and practice of cardiology, enhance cardiovascular health, and inform health care policy. JAMA Cardiology will focus on all aspects of cardiovascular medicine, including epidemiology and prevention, diagnostic ...Key Points. Question What are the characteristics and outcomes of patients with heart transplant who are infected with coronavirus disease 2019 (COVID-19)?. Findings In this case series of 28 patients who had received heart transplant in a large academic center, the case fatality rate among patients infected with COVID-19 was 25%. . Cardiovascular comorbidities …JAMA Cardiology. Full Text. Abstract Importance Familial hypercholesterolemia (FH) is an underdiagnosed and undertreated genetic disorder that leads to premature morbidity and mortality due to atherosclerotic cardiovascular disease. Familial hypercholesterolemia affects 1 in 200 to 250 people around the world of every race and ethnicity.These data underscore the importance of AF prevention in women. Introduction. Atrial fibrillation (AF) is the most prevalent arrhythmia in the world and is associated with an increased risk of stroke, heart failure, and overall mortality. 1 As the population ages, the number of patients with AF is expected to burgeon.JAMA Cardiology. Key Points. Question Is COVID-19 vaccination linked to the occurrence of myocarditis? Findings In this study of 7 patients with acute myocarditis, 4 occurred within 5 days of COVID-19 vaccination between February 1 and April 30, 2021. All 4 ...JAMA Cardiology. Key Points. Question Can coronary artery calcium score identify individuals likely to derive net benefit from aspirin therapy for primary prevention of atherosclerotic cardiovascular disease? Findings In this cohort study, using participants from the Dallas Heart Study cohort who were free from atherosclerotic cardiovascular ...Key Points. Question How much would the highly atherogenic lipoprotein(a) have to be lowered to decrease the coronary heart disease outcomes in the same range as observed for a lowering of low-density lipoprotein cholesterol by 38.67 mg/dL?. Findings In this mendelian randomization analysis, it was estimated that lipoprotein(a) would have to …In this issue of JAMA Cardiology, Jaeger and colleagues 1 report a secondary analysis of the Systolic Blood Pressure Intervention Trial (SPRINT) study evaluating the association of long-term intensive blood pressure (BP) treatment with cardiovascular and all-cause mortality. Sadly, the robust reduction in mortality seen in the intensive treatment group …Jan 1, 2021 · Myocarditis is a significant cause of sudden cardiac death in competitive athletes and can occur with normal ventricular function. 1 Recent studies have raised concerns of myocardial inflammation after recovery from coronavirus disease 2019 (COVID-19), even in asymptomatic or mildly symptomatic patients. 2 Our objective was to investigate the use of cardiac magnetic resonance (CMR) imaging in ... This cohort study performs a post hoc analysis of data for US and Australian participants in the Aspirin in Reducing Events in the Elderly (ASPREE) clinical trial to determine the association between level of high-density lipoprotein cholesterol and increased fracture risk in healthy older adults. Aug 1, 2022 · Piepoli MF , Hoes AW , Agewall S , et al; ESC Scientific Document Group. 2016 European guidelines on cardiovascular disease prevention in clinical practice: the Sixth Joint Task Force of the European Society of Cardiology and other societies on cardiovascular disease prevention in clinical practice (constituted by representatives of 10 societies and by invited experts): developed with ... Additionally, information on cardiac arrest causative mechanism (presumed cardiac, respiratory, drug overdose, and other mechanism) and as to whether bystander cardiopulmonary resuscitation (CPR) or defibrillation … JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Additionally, information on cardiac arrest causative mechanism (presumed cardiac, respiratory, drug overdose, and other mechanism) and as to whether bystander cardiopulmonary resuscitation (CPR) or defibrillation … JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JAMA Cardiology. JAMA Guide to Statistics and Methods. Overlap Weighting—A Propensity Score Method That Mimics Attributes of a Randomized Clinical Trial. Laine E. Thomas, PhD; Fan Li, PhD; Michael J. Pencina, PhD. JAMA. Original Investigation. Association of ACEI or ARB Use With COVID-19 Diagnosis and Mortality.JAMA Cardiology. Key Points. Question Can readily available electrocardiogram (ECG) data be used to train a high-performing convolutional neural network (CNN) across a large range of 12-lead ECG diagnoses when compared with clinical standards of care? The JAMA Cardiology Patient Page is a public service of JAMA Cardiology. The information and recommendations appearing on this page are appropriate in most instances, but they are not a substitute for medical diagnosis. For specific information concerning your personal medical condition, JAMA Cardiology suggests that you consult your physician ... Improvement in cardiovascular outcomes has slowed, and the obesity epidemic that contributed to cardiovascular disease continues. Given the current uncertain state of knowledge, neither patients nor physicians can be confident that omega-3 fatty acids have any health benefits, yet in 2019 the global market for omega-3 fatty acids reached $4.1 ...JAMA Network is a consortium of peer-reviewed medical publications that includes JAMA® and the JAMA Network journals. JAMA Cardiology does not hold itself responsible for statements made by any contributor. All articles published, including opinion articles, represent the views of the authors and do not reflect the policy of the Journal, the ...Two articles published in JAMA Cardiology from 2 academic hospitals in Wuhan, China, the epicenter of the COVID-19 pandemic, 10,11 support these concepts while also providing novel insights into the incidence and consequences of myocardial injury associated with SARS-CoV-2.Feb 7, 2020 · This cohort study, conducted from January 20, 2020, to February 10, 2020, in Wuhan, China, explores the prevalence of cardiac injury in hospitalized patients with COVID-19 and its association with mortality. Key Points. Question Can a deep learning model using routinely acquired outpatient 12-lead electrocardiograms (ECGs) in sinus rhythm predict the presence of atrial fibrillation (AF) within 31 days across diverse populations?. Findings In this prognostic study, a model trained on data from 2 large Veterans Affairs (VA) hospital networks predicted AF with … This secondary analysis of a randomized clinical trial examines whether longitudinal increases in high-sensitivity C-reactive protein levels during 16 weeks after an acute coronary syndrome are associated with increased risk of a major adverse cardiac event, cardiovascular death, and all-cause... Disclaimer: Dr Mehran is Associate Editor of JAMA Cardiology, but she was not involved in any of the decisions regarding review of the manuscript or its acceptance. References 1. Kirchhof P , Benussi S , Kotecha D , et al; ESC Scientific Document Group. 2016 ESC guidelines for the management of atrial fibrillation developed in ...Key Points. Question Is myocardial inflammation present in patients recently recovered from COVID-19 and is this associated with tissue characterization abnormalities and blood biomarkers?. Findings In this cohort study of 47 participants recently recovered from COVID-19, myocardial inflammation was identified in a small proportion based on focal …Key Points. Question In statin-treated patients at high cardiovascular risk with elevated triglyceride levels and low levels of high-density lipoprotein cholesterol treated with ω-3 fatty acids, are achieved levels of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) associated with cardiovascular outcomes?. Findings In a secondary analysis of a …Key Points. Questions What is the 20-year prevalence of food insecurity among individuals with cardiovascular disease or cardiometabolic risk factors, and does this prevalence differ across racial and ethnic groups?. Findings In this cross-sectional study of noninstitutionalized US adults from 1999 through 2018, food insecurity increased over …Our acceptance rate of 7% for original science manuscripts is on par with the other major journals in our field. After only 3 years of publishing, JAMA Cardiology’s impact factor was 11.9 in 2019 (which is reported for 2018). As anticipated, the continuous flow of manuscripts has increased the workload of our very busy editors, but we relish ...JAMA Cardiology. Editor's Comment. A Brief Window to Rethink Emergency Care. Melinda B. Buntin, PhD. JAMA Health Forum. We are in the midst of the coronavirus disease 2019 (COVID-19) pandemic and, as many clinicians across the globe, we are seeing firsthand the pain and death caused by COVID-19.Importance Increasing cardiology workforce diversity will expand the talent of the applicant pool and may reduce health care disparities.. Objective To assess US cardiology physician workforce demographics by sex and race/ethnicity in the context of the US population and the available pipelines of trainees.. Design, Setting, and Participants This cross-sectional study used data …Figure 1. Flow Diagram of Analyses. ASCVD indicates atherosclerotic cardiovascular disease; GRS, genetic risk score; Lp (a), lipoprotein (a); LDL-C, low-density lipoprotein cholesterol. To convert LDL-C to millimoles per liter, multiply by 0.0259; Lp (a) to milligrams per deciliter, divide by 2.4. Figure 2.JAMA Cardiology. Key Points. Question Is a ticagrelor-based or prasugrel hydrochloride–based strategy superior for patients with acute coronary syndrome treated with percutaneous coronary intervention? Findings In this prespecified subgroup analysis of a randomized clinical trial, among ...JAMA Cardiology is an international peer-reviewed journal and the definitive journal for clinical investigators, clinicians, and trainees in cardiovascular medicine … JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Writing Committee Members, Otto CM , Nishimura RA , Bonow RO , et al. 2020 ACC/AHA guideline for the management of patients with valvular heart disease: executive summary: a report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. JAMA Cardiology—The Year in Review, 2023. Robert O. Bonow, MD, MS JAMA Cardiol March 13, 2024. Original Investigation. Quantitative Coronary Angiography vs ... Piepoli MF , Hoes AW , Agewall S , et al; ESC Scientific Document Group. 2016 European guidelines on cardiovascular disease prevention in clinical practice: the Sixth Joint Task Force of the European Society of Cardiology and other societies on cardiovascular disease prevention in clinical practice (constituted by representatives of …Two articles published in JAMA Cardiology from 2 academic hospitals in Wuhan, China, the epicenter of the COVID-19 pandemic, 10,11 support these concepts while also providing novel insights into the incidence and consequences of myocardial injury associated with SARS-CoV-2. Beyond this recommendation, however, some investigators have called for broader de-risking of patients with a CAC score of 0, suggesting that even those with familial hypercholesterolemia and a CAC score of 0 may not need add-on therapy beyond statins and ezetimibe. 7 The article by Mortensen et al 8 in this issue of JAMA Cardiology should give ... Disclaimer: Dr Sabatine is Deputy Editor of JAMA Cardiology, but he was not involved in any of the decisions regarding review of the manuscript or its acceptance. References 1. Beltrán-Sánchez H , Harhay MO , Harhay MM , McElligott S . Prevalence and trends of metabolic syndrome in the adult U.S. population, 1999-2010. JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Figure 1. Flow Diagram of Analyses. ASCVD indicates atherosclerotic cardiovascular disease; GRS, genetic risk score; Lp (a), lipoprotein (a); LDL-C, low-density lipoprotein cholesterol. To convert LDL-C to millimoles per liter, multiply by 0.0259; Lp (a) to milligrams per deciliter, divide by 2.4. Figure 2.Key Points. Question What are the trends in characteristics and outcomes of adult heart transplant after implementation of the new heart allocation policy on October 18, 2018?. Findings In this cohort study of 15 631 patients, with the heart allocation policy change, higher-risk recipients are now undergoing transplant, with higher rates of bridging with …Key Points. Question Is the clinical benefit of low-density lipoprotein cholesterol (LDL-C) lowering preserved in patient populations starting with LDL-C levels averaging 1.8 mmol/L (70 mg/dL) or less, and is LDL-C lowering safe in such patients?. Findings In this meta-analysis, for statins and nonstatins, the risk of major vascular …A, Percentage of patients who achieved low-density lipoprotein cholesterol (LDL-C) levels less than 70 mg/dL and less than 55 mg/dL (to convert to millimoles per liter, multiply by 0.0259) at baseline and 2 years of follow-up in the Getting to an Improved Understanding of Low-Density Lipoprotein Cholesterol and Dyslipidemia Management (GOULD) registry.JAMA Cardiology. Key Points. Question Can readily available electrocardiogram (ECG) data be used to train a high-performing convolutional neural network (CNN) across a large range of 12-lead ECG diagnoses when compared with clinical standards of care? Bonow RO , Carabello BA , Chatterjee K , et al; American College of Cardiology; American Heart Association Task Force on Practice Guidelines (Writing Committee to revise the 1998 guidelines for the management of patients with valvular heart disease); Society of Cardiovascular Anesthesiologists. PMID: 32730619. PMCID: PMC7385689. DOI: 10.1001/jamacardio.2020.3557. Abstract. Importance: Coronavirus disease 2019 …Key Points. Question Does an entirely remote hypertension and hypercholesterolemia program implemented across a large diverse health network help ensure equal access to care?. Findings In this cohort study including 10 803 patients with blood pressure and/or cholesterol levels above guideline-recommended targets, remote medication titration management was significantly …Key Points. Question What are the efficacy and safety of omecamtiv mecarbil for the treatment of patients with severe heart failure (HF)?. Finding In this post hoc analysis of data from 8232 patients with symptomatic HF enrolled in the Global Approach to Lowering Adverse Cardiac Outcomes Through Improving Contractility in Heart Failure …Key Points. Question In patients diagnosed with atrial fibrillation before 66 years of age, what is the prevalence of disease-associated variants in susceptibility genes for inherited cardiomyopathy and arrhythmia syndromes?. Findings In this cohort study, among 1293 participants who underwent whole genome sequencing, disease-associated rare … JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JAMA Cardiology. Editor's Comment. A Brief Window to Rethink Emergency Care. Melinda B. Buntin, PhD. JAMA Health Forum. We are in the midst of the coronavirus disease 2019 (COVID-19) pandemic and, as many clinicians across the globe, we are seeing firsthand the pain and death caused by COVID-19.Key Points. Question Is there an association between normal systolic blood pressure values as currently defined and atherosclerotic cardiovascular disease among persons without traditional cardiovascular disease risk factors?. Findings In this cohort study including 1457 participants without atherosclerotic cardiovascular disease, beginning with a systolic …A, Probability of the primary composite end point, with extrapolated mean event-free survival time at age 65 years of 6.2 years for placebo and 8.3 years for dapagliflozin (difference, 2.1 years; 95% CI, 0.8-3.3 years; P = .002).B, Probability of death from any cause, with mean extrapolated life expectancy of 9.1 years for placebo and 10.8 years for dapagliflozin (difference, 1.7 years; 95% …Disclaimer: Dr Thomas is the Assistant Editor for Statistics of JAMA Cardiology, Dr Hernandez is an Associate Editor for JAMA Cardiology, and Dr Fonarow is the Associate Editor of Health Care Quality and Guidelines for JAMA Cardiology, but they were not involved in any of the decisions regarding review of the manuscript or its acceptance.
Importance The Ross procedure as treatment for adults with aortic valve disease (AVD) has been the subject of renewed interest.. Objective To evaluate the long-term clinical and echocardiographic outcomes following the Ross procedure for the treatment of adults with AVD.. Design, Setting, and Participants This post hoc analysis of a randomized clinical …. Castles and coasters
Corresponding Author: Sadiya S. Khan, MD, MS, Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, 680 N Lake Shore Dr, 14-002, Chicago, IL 60611 ([email protected]). JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) This analysis of data from the 2016 Global Burden of Disease Study examines the national and province-level mortality, prevalence, and disability-adjusted life-years associated with cardiovascular disease in China from 1990 to 2016.JAMA Cardiology. Country. United States. Universities and research institutions in United States. Media Ranking in United States. Subject Area and Category. …Key Points. Question What is the temporal association between episodes of atrial fibrillation (AF) and ischemic stroke in patients with cardiac implantable electronic devices (CIEDs)?. Findings In this case-crossover study including 891 patients with CIEDs and ischemic stroke, multihour AF episodes raised the odds of stroke 3.7-fold for up to 30 days.Jan 1, 2021 · Myocarditis is a significant cause of sudden cardiac death in competitive athletes and can occur with normal ventricular function. 1 Recent studies have raised concerns of myocardial inflammation after recovery from coronavirus disease 2019 (COVID-19), even in asymptomatic or mildly symptomatic patients. 2 Our objective was to investigate the use of cardiac magnetic resonance (CMR) imaging in ... JAMA Cardiology. Key Points. Question Is COVID-19 vaccination linked to the occurrence of myocarditis? Findings In this study of 7 patients with acute myocarditis, 4 occurred within 5 days of COVID-19 vaccination between February 1 and April 30, 2021. All 4 ...Long-term use of a left ventricular assist device for end-stage heart failure. N Engl J Med. 2001;345 (20):1435-1443. PubMed Google Scholar Crossref. Miller LW, Pagani FD, Russell SD, et al; HeartMate II Clinical Investigators. Use of a continuous-flow device in …Importance One in 5 US adults older than 60 years takes fish oil supplements often for heart health despite multiple randomized clinical trials showing no data for cardiovascular benefit for supplement-range doses. Statements on the supplement labels may influence consumer beliefs about health benefits. Objectives To evaluate health claims made on the labels of fish oil …Using clinical registry data from 7 Mass General Brigham hospitals and affiliated practices, we isolated 2 cohorts of patients with cholesterol testing on 2 or more occasions who were 20 to 39 years old at the time of a qualifying LDL-C value between 2005 and 2018: cohort 1 included individuals with an LDL-C value of 190 mg/dL or …Key Points. Question What is the diagnostic and prognostic value of stress cardiovascular magnetic resonance imaging (CMR) for the evaluation of stable chest pain?. Findings In this systematic review and meta-analysis pooling 74 470 patients with stable chest pain over 381 357 person-years of follow-up, stress CMR yielded high diagnostic accuracy and … A, Composite outcome, B, all-cause mortality, and C, major cardiovascular disease (CVD) adjusted for age, sex, urban or rural residence, country income level, education level, household wealth index, smoking status, physical activity, depression, baseline chronic diseases, physical impairments, and a random intercept for clustering of centers. In this issue of JAMA Cardiology, Lindner and colleagues 4 report on 39 autopsy cases of patients with COVID-19 in whom pneumonia was the clinical cause of death in 35 of 39 (89.7%). While histopathologic evaluation did not meet criteria seen in acute myocarditis, there was evidence of virus present in the heart in 24 of 39 patients (61.5% ... Importance Previous studies of basic cardiopulmonary resuscitation (CPR) indicate that both chest compression rate (CCR) and chest compression depth (CCD) each are associated with survival probability after out-of-hospital cardiac arrest. However, an optimal CCR-CCD combination has yet to be identified, particularly with respect to age, … JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Writing Committee Members, Otto CM , Nishimura RA , Bonow RO , et al. 2020 ACC/AHA guideline for the management of patients with valvular heart disease: executive summary: a report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. JAMA Cardiology ’s impact factor was 30.2 in 2022 (which is reported for 2021). The journal’s weekly online content is now delivered to more than 97 000 readers, with 3.3 million annual article views and downloads. We maintain an active presence on social media, with an increase during the past year to more than 114 000 Twitter and Facebook ... A, Probability of the primary composite end point, with extrapolated mean event-free survival time at age 65 years of 6.2 years for placebo and 8.3 years for dapagliflozin (difference, 2.1 years; 95% CI, 0.8-3.3 years; P = .002).B, Probability of death from any cause, with mean extrapolated life expectancy of 9.1 years for placebo and 10.8 years for dapagliflozin (difference, 1.7 years; 95% ….